Ahead of the match Lee Sedol explained to the BBC: "Playing against a machine is very different from an actual human opponent. Normally, you can sense your opponent's breathing, their energy. And lots of times you make decisions which are dependent on the physical reactions of the person you're playing against. With a machine, you can't do that".
While AlphaGo has a continuously playing (and thinking) backup running in the background on Google's data centers in the west of the US, Lee Sedol needs to analyse, process and digest all experiences, patterns, moves, and positions of the previous game in his sleep (without a backup clone who can take over insensibly in case things may become momentarily too heavy and difficult).
Hassabis explained to the press: "the DeepMind team will enter this match, in which everything is possible, open minded and unprejudiced". Lee Sedol will begin the match, however, on the basis of the Fan Hui games and above all have the strong feeling that he surely would have exploited AlphaGo's weaknesses (and simply never would have played some of Fan Hui's overplays).
One thing is for sure: the match between AlphaGo and Lee Sedol will be an extremely important chapter in the history of artificial intelligence. Experts and official distinguished ones in AI all agree that if AlphaGo wins this match, that will open a new door and will be a completely new chapter in the future development of AI.
For many, that will be a very bitter pill to swallow and hard to digest turning point: that our superior intuition when judging a Go-position and our immense creativity to come up with the most effective move, allowing all stones on the Go-board to work together and cooperate as good and efficient as possible, will be completely overpowered and superseded by a computer program.
[Deep Learning AlphaGo vs. Lee Sedol Match Overview]